Technical Program

Paper Detail

Paper:	SA-PM-SS1.3
Session:	The Use of Shape in Biomedical Imaging
Time:	Saturday, April 8, 15:30 - 15:50
Presentation:	Special Session Oral
Title:	Statistics of populations of images and its embedded objects: Driving applications in neuroimaging
Authors:	Guido Gerig; University of North Carolina at Chapel Hill
	Sarang Joshi; University of North Carolina at Chapel Hill
	Tom Fletcher; University of Utah
	Kevin Gorczowski; University of North Carolina at Chapel Hill
	Shun Xu; University of North Carolina at Chapel Hill
	Stephen M. Pizer; University of North Carolina at Chapel Hill
	Martin Styner; University of North Carolina at Chapel Hill
Abstract:	Work in progress towards modeling shape statistics of multi-object complexes is presented. Constraints defined by the set of objects such as a compact representation of object shape relationships and correlation of shape changes might have advantages for automatic segmentation and group discrimination. We present a concept for statistical multi-object modeling and discuss the major challenges which are a reduction to a small set of descriptive features, calculation of mean and variability via curved statistics, the choice of aligning sets of multiple objects, and the problem of describing the statistics of object pose and object shape and their interrelationship. Shape modeling and analysis is demonstrated with an application to a longitudinal autism study, with shape modeling of sets of 10 subcortical structures in a population of 20 subjects.

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