Technical Program

Paper Detail

Paper:	SA-AM-SS1.3
Session:	Towards Vertical Integration of Biomedical Data
Time:	Saturday, April 8, 10:10 - 10:30
Presentation:	Special Session Oral
Title:	Cancer Disease: Integrative Modelling Approaches
Authors:	Helen Byrne; University of Nottingham
	Markus Owen; University of Nottingham
	Tomas Alarcon; University College London
	Philip Maini; University of Oxford
Abstract:	Cancer is a complex disease in which a variety of phenomena interact over a wide range of spatial and temporal scales. In this article a theoretical framework will be introduced that is capable of linking together such processes to produce a detailed model of vascular tumour growth. The model is formulated as a hybrid cellular automaton and contains submodels that describe subcellular, cellular and tissue level features. Model simulations will be presented to illustrate the effect that coupling between these different elements has on the tumour's evolution and its response to chemotherapy.

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