Imaging the Mouse

Date: Thursday, April 13, 2007

Presented by

Mark Henkelman

Dr. R. Mark Henkelman is a Professor in the Departments of Medical Biophysics and Medical Imaging at the University of Toronto. He is a Senior Scientist in Imaging Research at Sunnybrook Health Sciences Centre where his research has focused on expanding the use of magnetic resonance imaging further into diagnosis and also into the management of therapy for cancer. He is a Senior Scientist and Director of the Mouse Imaging Centre (MICe) at the Hospital for Sick Children. As Director, Dr. Henkelman’s research is focused on building the Mouse Imaging Centre (MICe) with high-field magnetic resonance imaging microscopy, ultrasound biomicroscopy, micro computed tomography, and optical techniques. With these imaging tools, MICe will screen randomly mutagenized mice to look for phenotypes that represent human diseases and will take established human disease models in mice and use imaging to follow the progression of disease and response to treatment over time. Preliminary results have shown that imaging has a major contribution to make to phenotyping genetic variants and to characterizing mouse models. The Mouse Imaging Centre (MICe) is a major new centre that became operational in 2001. It is staffed by an exciting team of 25 investigators with expertise in imaging techniques, computer science, engineering, imaging processing, developmental biology and mouse pathology. Dr. Henkelman is a co-author on 10 patents, over 265 publications, 440 abstracts and numerous presentations worldwide. He holds a Tier 1 Canada Research Chair in Imaging awarded by the Government of Canada. In 1998, he was awarded a Gold Medal from the International Society of Magnetic Resonance in Medicine. In 2005, he was appointed a Fellow of the Royal Society of Canada and a University Professor, the highest honor that the University of Toronto awards to its faculty. For further information, please visit: http://www.mouseimaging.ca