Technical Program

Paper Detail

Paper:	TH-PM-PS2.2
Session:	Diffusion Tensor Imaging
Time:	Thursday, April 6, 15:20 - 16:40
Presentation:	Poster
Title:	Statistical Modeling and EM Clustering of White Matter Fiber Tracts
Authors:	Mahnaz Maddah; CSAIL, Massachusetts Institute of Technology
	W. Eric L. Grimson; CSAIL, Massachusetts Institute of Technology
	Simon K. Warfield; Brigham and Women's Hospital / Harvard Medical School
Abstract:	A statistical model of the fiber bundles is calculated as the average and standard deviation of a parametric representation of the fiber tracts, using the coefficients of the 3D quintic B-spline representation of the tracts. An atlas of the fiber tracts is constructed by averaging the bundle models over a population with the fiber tracts mapped onto the atlas coordinate. Using the model representation and with the atlas as the prior map, expectation-maximization (EM) is performed to cluster the fiber tracts in a mixture model framework. As an application, the method is applied to cluster the corpus callosum fiber tracts into its subdivisions and to calculate quantitative parameters for each region.

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