Technical Program

Paper Detail

Paper:	SA-PM-OS4.3
Session:	Multimodality and Novel Imaging Methods
Time:	Saturday, April 8, 17:20 - 17:40
Presentation:	Oral
Title:	Compensating for Patient Respiration in PET/CT Imaging with the Registered and Summed Phases (RASP) Procedure
Authors:	Paul Kinahan; University of Washington
	Lawrence MacDonald; University of Washington
	Lydia Ng; Allen Institute for Brain Science
	Adam Alessio; University of Washington
	W. Paul Segars; The Johns Hopkins University
	Benjamin Tsui; The Johns Hopkins University
	Sayan Pathak; Allen Institute for Brain Science
Abstract:	PET/CT imaging has introduced new challenges in accurate quantitation of lung nodules due to respiratory motion and mismatches in CT-based attenuation correction (CTAC). We used Monte Carlo simulations to investigate how respiratory-correlated CTAC can be optimized to account for mis-registration between the AC data and the PET data due to respiratory motion. This step also allows compensating for increased emission noise in respiratory respiratory-gated PET images by non-rigid image registration of the CTAC phases. These registration parameters are then applied to the attenuation-corrected PET phase images, which are then summed to reduce noise. A significant increase in the final PET SNR is demonstrated.

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