ISBI 2006: IEEE 2006 International Symposium on Biomedical Imaging, April 6-9, 2006, Crystal Gateway Marriott, Arlington, Virginia, U.S.A.

Technical Program

Paper Detail

Paper:SU-AM-PS4.8
Session:Image Segmentation, Retrieval and Analysis
Time:Sunday, April 9, 10:50 - 12:10
Presentation: Poster
Title: Fuzzy Versus Hard Hidden Markov Chains Segmentation for Volume Determination and Quantitation in Noisy PET Images
Authors: Mathieu Hatt; LaTIM INSERM U560 
 Nicolas Boussion; LaTIM INSERM U560 
 Frederic Lamare; LaTIM INSERM U560 
 Christophe Collet; ENSPS LSIIT UMR CNRS 7005 
 Fabien Salzenstein; InESS CNRS/ULP - UMR 7163 
 Christian Roux; LaTIM INSERM U650 
 Yves Bizais; LaTIM INSERM U560 
 Catherine Cheze-Le Rest; LaTIM INSERM U560 
 Dimitris Visvikis; LaTIM INSERM U560 
Abstract: Accurate volume contouring in PET is crucial for quantitation in oncology applications. The objective of our study was to compare the performance of two algorithms for automatic lesion volume delineation that permit noise modelling and have not previously been applied to PET data; namely the Hidden Markov Chains (HMC) model and a novel version: Fuzzy HMC. Both models take into account noise, voxel’s intensity and spatial correlation, in order to classify a voxel as “background” or “functional volume”. In comparison to HMC which only models uncertainty, the novelty of the fuzzy model consists of the inclusion of an estimation of imprecision. The performance of both models was compared using realistic simulated images. Results demonstrate that FHMC performs better than HMC in both quantitation as well as functional volume determination under different imaging conditions.



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