Technical Program

Paper Detail

Paper:	FR-PM-OS1.6
Session:	Optical and Infrared Imaging
Time:	Friday, April 7, 17:00 - 17:20
Presentation:	Oral
Title:	A Statistical Method for Inverting the Born Ratio
Authors:	Damon Hyde; Northeastern University
	Eric Miller; Northeastern University
	Dana H. Brooks; Northeastern University
	Vasilis Ntziachristos; Massachusetts General Hospital / Harvard Medical School
Abstract:	We examine a statistical solution to the problem of Fluorescence Molecular Tomography (FMT) using the Born ratio. Experimentally verified noise models for the fluorescence and excitation signals are combined to generate a stochastic model for the Born ratio. This model is then utilized within a maximum likelihood (ML) framework to obtain a fixed point iteration about a linear least squares problem. Results for experimental data are shown, including phantoms implanted within a small animal, and in-vivo data using an exogenous probe.

ISBI 2006 is sponsored by

and organized in cooperation with