Technical Program

Paper Detail

Paper:	FR-PM-OS3.5
Session:	Image Registration
Time:	Friday, April 7, 16:40 - 17:00
Presentation:	Oral
Title:	Brain Shift Analysis for Deep Brain Stimulation Surgery
Authors:	Muhammad Khan; Georgia Institute of Technology
	Klaus Mewes; Emory University
	Oskar Škrinjar; Georgia Institute of Technology
Abstract:	Deep brain stimulation (DBS) surgery can significantly improve the quality of life for patients suffering from movement disorders, but the outcome of the surgery greatly depends on the implantation accuracy of the deep brain stimulator. A few millimeter shift in the mid brain region can influence the results because the pre-operative planning is based on the assumption that anatomical structures do not move between the pre-operative image scan time and the time of operation. We studied 15 cases of DBS surgery for possible brain shift between preop and postop 3D MRI scans. Brain shift of up to 3.8mm was measured after rigidly aligning the preop with postop images. The rigid registration algorithm has sub-voxel accuracy (registration error of less than 1mm), and it automatically recovers any rotation around the three axes along with significant translations in the three directions. The brain shift measurements were compared to relevant intra and post operative parameters.

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