Technical Program

Paper Detail

Paper:	TH-PM-PS2.7
Session:	Diffusion Tensor Imaging
Time:	Thursday, April 6, 15:20 - 16:40
Presentation:	Poster
Title:	Estimating Myocardial Fiber Orientations by Template Warping
Authors:	Hari Sundar; University of Pennsylvania
	Dinggang Shen; University of Pennsylvania
	George Biros; University of Pennsylvania
	Harold Litt; University of Pennsylvania
	Christos Davatzikos; University of Pennsylvania
Abstract:	Myocardial fiber orientations are an important element for accurate modeling of cardiac electromechanics. However it is extremely difficult to estimate these directly in vivo with current imaging techniques. Most current methods for cardiac modeling use synthetic models of fiber orientation which may fail to capture subtle variations of fiber orientations in different hearts. We present a method to map the fiber orientations obtained from diffusion tensors from a template onto patient-specific cardiac geometry, using elastic registration followed by a reorientation of the diffusion tensors based on the local rotation component of the transformation. The effectiveness of the diffusion tensor mapping is validated on a set of diffusion tensor imaging datasets obtained from 19 canine subjects. The algorithm was able to map the diffusion tensors effectively for both healthy and failing hearts.

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