ISBI 2006: IEEE 2006 International Symposium on Biomedical Imaging, April 6-9, 2006, Crystal Gateway Marriott, Arlington, Virginia, U.S.A.

Technical Program

Paper Detail

Paper:SA-PM-PS3.11
Session:Functional, Dynamic and Parametric Imaging
Time:Saturday, April 8, 13:30 - 14:50
Presentation: Poster
Title: Variance Controlled Shear Stiffness Images for MRE Data
Authors: Joyce McLaughlin; Rensselaer Polytechnic Institute 
 Daniel Renzi; Rensselaer Polytechnic Institute 
 Jeong Rock Yoon; Rensselaer Polytechnic Institute 
 Richard Ehman; Mayo Clinic 
 Armando Manduca; Mayo Clinic 
Abstract: In the Magnetic Resonance Elastography experiment we consider a harmonically oscillating mechanical force applied to the boundary of a phantom and synchronized with the motion encoding gradient. The phantom is symmetric in the direction of the applied mechanical force and the vector component in that direction decouples from the other components and satisfies a Helmholtz equation. We present a local inversion method to determine the shear wave speed that: (1) treats the phase and amplitude of the data differently; (2) computes derivatives of the data by using statistically justified filtering; and (3) varies filters according to SNR. We test our methods on data from Mayo Clinic and recover the position and stiffness of a 3mm diameter inclusion.



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