ISBI 2006: IEEE 2006 International Symposium on Biomedical Imaging, April 6-9, 2006, Crystal Gateway Marriott, Arlington, Virginia, U.S.A.

Technical Program

Paper Detail

Paper:FR-PM-PS3.12
Session:Image Guided Diagnosis, Surgery and Therapy
Time:Friday, April 7, 13:30 - 14:50
Presentation: Poster
Title: Hidden Seed Reconstruction from C-ARM Images in Brachytherapy
Authors: Ryan Kon; The Johns Hopkins University 
 Ameet Jain; The Johns Hopkins University 
 Gabor Fichtinger; The Johns Hopkins University 
Abstract: There has been a pressing clinical need for adaptive intra-operative dosimetry in the delivery of prostate brachytherapy implants. The missing prerequisite is the robust matching of the seeds across multiple C-arm images. This is further aggravated since seeds are invariably hidden in each image. We present a solution to recover these hidden seeds in this paper. A network flow formulation of the problem is proposed, where the desired solution is obtained (in polynomial time) by computing the flow with minimum cost. Phantom experiments show that using four X-ray images, on an average 99.8% of the seeds are recovered correctly, while simulations indicate that our algorithm is robust to segmentation errors of up to 1 mm and hidden seed rate of at least 8%. The results show strong feasibility and clinical data collection is currently underway.



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