ISBI 2006: IEEE 2006 International Symposium on Biomedical Imaging, April 6-9, 2006, Crystal Gateway Marriott, Arlington, Virginia, U.S.A.

Technical Program

Paper Detail

Paper:SA-PM-OS2.8
Session:Functional Brain Imaging
Time:Saturday, April 8, 17:40 - 18:00
Presentation: Oral
Title: Robust Constrained NonGaussian FMRI Detection
Authors: Mukund Desai; C. S. Draper Laboratory 
 Rami Mangoubi; C. S. Draper Laboratory 
 David Kennedy; Massachusetts General Hospital 
Abstract: For fMRI detection, it is desirable to have sensitive detectors for enhanced performance in low SNR environment. This sensitivity, usually captured through learning of associated models, comes at the price of increased false alarms. In this paper, we address the issue of robustness to false alarm while maintaining sensitivity by providing the analytical framework for incorporating prior information in the form of constraints in a non-Gaussian setting. We show that the impact on the decision statistic of incorporating constraints is simply captured through a simple modification of the unconstrained detector's statistic. The computational burden of the constrained and unconstrained detectors are thus similar. The performance of the new constrained detector is shown on fMRI data to provide superior performance when compared the conventional CFAR detector. Keywords: Constraint, detector, robust,fMRI, non-Gaussian, Gaussian, CFAR.



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