ISBI 2006: IEEE 2006 International Symposium on Biomedical Imaging, April 6-9, 2006, Crystal Gateway Marriott, Arlington, Virginia, U.S.A.

Technical Program

Paper Detail

Paper:SU-AM-PS2.5
Session:Optical Imaging and Analysis
Time:Sunday, April 9, 10:50 - 12:10
Presentation: Poster
Title: Quantitative Analysis of Immunofluorescent Retinal Images
Authors: Jiyun Byun; University of California, Santa Barbara 
 Nhat Vu; University of California, Santa Barbara 
 Baris Sumengen; University of California, Santa Barbara 
 B. S. Manjunath; University of California, Santa Barbara 
Abstract: We present a novel method to quantitatively analyze confocal microscope images of retinas. We automatically detect nuclei within the outer nuclear layer (ONL) in a retinal image. Based on nuclei detection results, we also automatically measure the thickness of the ONL and the local cell density within the ONL. These measurements provide the first thorough quantitative analysis of retinal images. Our results not only verify previous conclusions about retinal restructuring during detachment, but also provide biologists with significant information about the regional responses in the ONL.



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