Technical Program

Paper Detail

Paper:	SU-AM-SS1.4
Session:	Optical Imaging from Ballistic to Diffusion Regimes
Time:	Sunday, April 9, 10:30 - 10:50
Presentation:	Special Session Oral
Title:	High-Resolution Photoacoustic Tomography In Vivo
Authors:	Lihong Wang; Texas A&M University
	Meng-Lin Li; Texas A&M University
	Hao Zhang; Texas A&M University
	Konstantin Maslov; Texas A&M University
	George Stoica; Texas A&M University
Abstract:	An in vivo backward-mode photoacoustic microscope was recently developed that employs a high frequency, broadband, large numerical aperture (NA) focused ultrasonic transducer to provide high resolution and high sensitivity. However, out of focus region, the limited depth of focus deteriorates the image quality significantly. Based on a virtual-detector concept, we devise and implement a synthetic aperture focusing technique in combination with coherence weighting to overcome this drawback. This technique improves the –6-dB lateral resolution from 50–265 microns to 46–55 microns and increases the SNR by up to 23 dB. In vivo experiments show that the technique provides a clearer representation of the vascular distribution in the dorsal dermis of a rat.

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